The Anti-IGFBP7 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0266) is a cutting-edge research tool designed for the detection and analysis of IGFBP7 protein in various biological samples. IGFBP7, also known as Insulin-like Growth Factor-Binding Protein 7, is a key regulator of cell growth, differentiation, and apoptosis, making it an important target in cancer research and other disease contexts.This antibody, developed with advanced chimeric recombinant technology, offers high specificity and sensitivity in detecting IGFBP7, allowing for precise and accurate results in Western blot applications.
With its superior reactivity with human samples, researchers can confidently use this antibody for studying the role of IGFBP7 in cancer progression, metastasis, and potential therapeutic targeting.By utilizing the Anti-IGFBP7 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0266), researchers can delve into the intricate mechanisms of IGFBP7 signaling pathways, uncovering its potential as a biomarker or therapeutic target in cancer therapy and beyond. Don't miss out on this powerful tool for advancing your research in immunology, oncology, and beyond.
SKU:
HDAB0266
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC422
Synonyms:
IBP-7, TAF, IGFBP-rP1, MAC25 protein
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).
