INDO Rabbit Monoclonal Antibody (CAB12125)
- SKU:
- CAB12125
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- IDO
- IDO-1
- INDO
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | INDO Rabbit Monoclonal Antibody |
SKU: | CAB12125 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IDO1 (P14902). |
Sequence: | IESG QLRE RVEK LNML SIDH LTDH KSQR LARL VLGC ITMA YVWG KGHG DVRK VLPR NIAV PYCQ LSKK LELP PILV YADC VLAN WKKK DPNK PLTY ENMD V |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 |
Synonyms: | IDO; INDO; IDO-1; IDO1 |
Positive Sample: | Mouse ovary |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol |
Calculated MW: | 45kDa |
Observed MW: | 42kDa |
This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.
Purification Method: | Affinity purification |
Gene ID: | 3620 |
Clone Number: | ARC0560 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |