The Anti-Human IgG3 Antibody (CAB19713) offered by Assay Genie is a valuable tool for researchers studying IgG3, a subclass of immunoglobulin G involved in immune responses. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications, allowing for the detection and analysis of IgG3 proteins in various cell types.IgG3 plays a crucial role in the immune system's defense against pathogens and is known for its ability to enhance phagocytosis and activate complement pathways.
Dysfunction in IgG3 levels or function has been implicated in various diseases, including autoimmune disorders, infectious diseases, and immune deficiencies. Therefore, research into IgG3 and its interactions is essential for developing novel therapeutic approaches for these conditions.With its specificity and reliability, the Anti-Human IgG3 Antibody (CAB19713) is a valuable asset for immunology and infectious disease research, providing researchers with a powerful tool for investigating the role of IgG3 in health and disease.
Product Name:
Human IgG3 Rabbit Monoclonal Antibody
SKU:
CAB19713
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IgG3 (P01860).
Blood microparticle, External side of plasma membrane, Extracellular exosome, Extracellular region, Extracellular space, Immunoglobulin complex, Circulating
Calculated MW:
41kDa
Observed MW:
60kDa
Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Involved in retina homeostasis. Located in blood microparticle and extracellular exosome.
Purification Method:
Affinity purification
Gene ID:
3502
Clone Number:
ARC2243
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from human plasma, using Human IgG3 Rabbit mAb (CAB19713) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
