The Anti-HSPA1A Antibody (CAB20819) from Assay Genie is a polyclonal antibody designed for research involving HSPA1A, a heat shock protein involved in cellular stress response. This antibody is raised in rabbits and is highly reactive with human samples, making it an ideal tool for detecting and analyzing HSPA1A expression in various cell types.HSPA1A, also known as HSP70, is a chaperone protein that plays a crucial role in protein folding and cellular protection during times of stress. It is implicated in various cellular processes, including protein quality control, signal transduction, and immune response regulation.
The Anti-HSPA1A Antibody allows researchers to study the function and expression of HSPA1A in immunology, cancer research, and other fields.By using the Anti-HSPA1A Antibody, researchers can gain valuable insights into the role of HSPA1A in cellular stress response, inflammation, and disease processes. This antibody is validated for use in Western blot applications, offering a reliable tool for studying HSPA1A in both basic research and clinical studies.
Product Name:
HSPA1A Polyclonal Antibody
SKU:
CAB20819
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 500-600 of human HSP70 (NP_005336.3).
Sequence:
KITI TNDK GRLS KEEI ERMV QEAE KYKA EDEV QRER VSAK NALE SYAF NMKS AVED EGLK GKIS EADK KKVL DKCQ EVIS WLDA NTLA EKDE FEHK RKEL E
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
Purification Method:
Affinity purification
Gene ID:
3303/3304
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using HSP70 Rabbit pAb (CAB20819) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 0.5s.
