The HRH3 Polyclonal Antibody (CAB3500) is designed for research involving HRH3, a G protein-coupled receptor that plays a key role in histamine signaling. The antibody, also raised in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. It specifically binds to the HRH3 protein, enabling precise detection and analysis in various cell types.The HRH3 receptor is involved in modulating neurotransmitter release and has implications in various neurological disorders, including schizophrenia and Alzheimer's disease.
By studying the activity of HRH3, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for drug development.Overall, the HRH3 Polyclonal Antibody (CAB3500) is a valuable tool for researchers interested in studying histamine receptors and their role in neuronal signaling pathways. Its high specificity and reactivity with human samples make it an ideal choice for investigating the functions of the HRH3 receptor in both normal physiology and disease states.
Product Name:
HRH3 Rabbit Monoclonal Antibody
SKU:
CAB3500
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HRH3 (Q9Y5N1).
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
Purification Method:
Affinity purification
Gene ID:
11255
Clone Number:
ARC2016
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using HRH3 Rabbit mAb (CAB3500) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
