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HOXB6 Rabbit Polyclonal Antibody (CAB20451)

SKU:
CAB20451
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
HOX2
HU-2
HOX2B
Hox-2.2
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:HOXB6 Rabbit Polyclonal Antibody
SKU:CAB20451
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-110 of human HOXB6 (NP_061825.2).
Sequence:SGYA DPLR HYPA PYGP GPGQ DKGF ATSS YYPP AGGG YGRA APCD YGPA PAFY REKE SACA LSGA DEQP PFHP EPRK SDCA Q
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:HOX2; HU-2; HOX2B; Hox-2.2; HOXB6
Positive Sample:293T,Mouse lung
Conjugate:Unconjugated
Cellular Localization:nucleus
Calculated MW:25kDa
Observed MW:25kDa

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.

Purification Method:Affinity purification
Gene ID:3216
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using HOXB6 Rabbit pAb (CAB20451) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 240s.

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