The HOXB6 Polyclonal Antibody (CAB20451) is a valuable tool for researchers studying the HOXB6 protein, a crucial transcription factor involved in developmental processes and cell differentiation. This antibody, produced in rabbits, is highly specific to human samples and has been extensively validated for use in immunohistochemistry and other experimental applications.HOXB6 is a member of the Homeobox gene family, which plays a key role in embryonic development and tissue patterning. Dysregulation of HOXB6 has been linked to various diseases, including cancer and developmental disorders.
By targeting the HOXB6 protein, researchers can investigate its function and potential therapeutic applications in these pathologies.This antibody offers researchers a reliable way to detect and analyze HOXB6 expression in a variety of cell types and tissues, providing valuable insights into its biological roles and molecular pathways. With its high specificity and sensitivity, the HOXB6 Polyclonal Antibody is an essential tool for advancing our understanding of HOXB6 biology and its potential implications in disease.
Product Name:
HOXB6 Rabbit Polyclonal Antibody
SKU:
CAB20451
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-110 of human HOXB6 (NP_061825.2).
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.
Purification Method:
Affinity purification
Gene ID:
3216
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HOXB6 Rabbit pAb (CAB20451) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 240s.
