The HOXB4 Polyclonal Antibody (CAB19699) is a valuable tool for researchers studying the HOXB4 protein, a transcription factor that plays a critical role in hematopoiesis and stem cell self-renewal. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for various research applications, including Western blotting.HOXB4 is known for its ability to promote the expansion of hematopoietic stem cells, making it a promising target for therapeutic interventions in conditions like hematologic malignancies and bone marrow failure syndromes.
By targeting HOXB4, researchers aim to manipulate stem cell function and enhance the efficacy of stem cell transplantation procedures.With the HOXB4 Polyclonal Antibody, researchers can accurately detect and quantify HOXB4 expression levels in different cell types and tissues, aiding in the understanding of its role in normal hematopoiesis and diseases affecting the blood and immune system. This antibody is a valuable tool for studies focused on stem cell biology, regenerative medicine, and the development of novel therapeutic strategies targeting HOXB4.
Product Name:
HOXB4 Rabbit Monoclonal Antibody
SKU:
CAB19699
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HOXB4 (P17483).
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.
Purification Method:
Affinity purification
Gene ID:
3214
Clone Number:
ARC2236
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HOXB4 Rabbit mAb (CAB19699) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
