HMGCS2 Rabbit Monoclonal Antibody (CAB19232)
- SKU:
- CAB19232
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- HMGCS2
- Hydroxymethylglutaryl-CoA synthase
- mitochondrial
- 3-hydroxy-3-methylglutaryl coenzyme A synthase
- 3-hydroxy-3-methylglutaryl-CoA synthase 2
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | HMGCS2 Rabbit Monoclonal Antibody |
SKU: | CAB19232 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 409-508 of human HMGCS2 (P54868). |
Sequence: | AFSY GSGL AASF FSFR VSQD AAPG SPLD KLVS STSD LPKR LASR KCVS PEEF TEIM NQRE QFYH KVNF SPPG DTNS LFPG TWYL ERVD EQHR RKYA RRPV |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | HMGCS2; Hydroxymethylglutaryl-CoA synthase; mitochondrial; 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl-CoA synthase 2 |
Positive Sample: | HepG2,Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 57kDa |
Observed MW: | 50kDa |
The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3158 |
Clone Number: | ARC2390 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |