Histone H2B Rabbit Monoclonal Antibody (CAB19812)
- SKU:
- CAB19812
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- H2B/S
- H2BFAiii
- H2BFT
- H2BK
Description
| Product Name: | Histone H2B Rabbit Monoclonal Antibody |
| SKU: | CAB19812 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse,Rat,Other (Wide Range Predicted) |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 47-126 of human Histone H2B (O60814). |
| Sequence: | KQVH PDTG ISSK AMGI MNSF VNDI FERI AGEA SRLA HYNK RSTI TSRE IQTA VRLL LPGE LAKH AVSE GTKA VTKY TSAK |
| Tested Applications: | WB IHC-P ELISA |
| Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
| Synonyms: | H2BK; H2B/S; H2BFT; H2BFAiii; HIST1H2BK; Histone H2B |
| Positive Sample: | HeLa,NIH/3T3,C6 |
| Conjugate: | Unconjugated |
| Cellular Localization: | cytosol, extracellular space, nucleoplasm, nucleus |
| Calculated MW: | 14kDa |
| Observed MW: | 17kDa |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family. The protein encoded is an antimicrobial protein with antibacterial and antifungal activity. Two transcripts that encode the same protein have been identified for this gene, which is found in the histone microcluster on chromosome 6p21.33.
| Purification Method: | Affinity purification |
| Gene ID: | 3017/8349 |
| Clone Number: | ARC2337 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates using Histone H2B Rabbit mAb (CAB19812) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s. |
Related Products
Formyl-Histone H2B-K108 Monoclonal Antibody (CAB0032)
Acetyl-Histone H2B-K5 Rabbit Polyclonal Antibody (CAB15621)
Acetyl-Histone H2B-K12 Rabbit Polyclonal Antibody (CAB15619)
Acetyl-Histone H2B-K15 Rabbit Polyclonal Antibody (CAB15622)
