The Hippocalcin (HPCA) Monoclonal Antibody (CAB19696) is a valuable tool for researchers studying the Hippocalcin protein, which is involved in various biological processes including neuronal signaling and calcium binding. This antibody, generated using hybridoma technology, exhibits high specificity and sensitivity in detecting Hippocalcin in human samples, making it ideal for use in Western blot and immunohistochemistry applications.Hippocalcin, a member of the neuronal calcium sensor protein family, plays a crucial role in regulating calcium-dependent signaling pathways in neurons.
Dysregulation of Hippocalcin has been linked to neurological disorders such as Alzheimer's disease and epilepsy, highlighting its importance in understanding brain function and disease pathology. By using the HPCA Monoclonal Antibody, researchers can investigate the localization and expression levels of Hippocalcin in various cell types and tissues, providing insights into its functional roles and potential therapeutic implications in neurological conditions.
Product Name:
Hippocalcin (HPCA) Rabbit Monoclonal Antibody
SKU:
CAB19696
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Hippocalcin (HPCA) (P84074).
The protein encoded by this gene is a member of neuron-specific calcium-binding proteins family found in the retina and brain. This protein is associated with the plasma membrane. It has similarities to proteins located in the photoreceptor cells that regulate photosignal transduction in a calcium-sensitive manner. This protein displays recoverin activity and a calcium-dependent inhibition of rhodopsin kinase. It is identical to the rat and mouse hippocalcin proteins and thought to play an important role in neurons of the central nervous system in a number of species.
Purification Method:
Affinity purification
Gene ID:
3208
Clone Number:
ARC2235
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Hippocalcin (HPCA) (HPCA) Rabbit mAb (CAB19696) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
