HDAC6 Rabbit Monoclonal Antibody (CAB3572)
- SKU:
- CAB3572
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CPBHM
- HD6
- JM21
- PPP1R90
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | HDAC6 Rabbit Monoclonal Antibody |
SKU: | CAB3572 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HDAC6 (Q9UBN7). |
Sequence: | MTST GQDS TTTR QRRS RQNP QSPP QDSS VTSK RNIK KGAV PRSI PNLA EVKK KGKM KKLG QAME EDLI VGLQ GMDL NLEA EALA GTGL VLDE QLNE FHCL |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | HD6; JM21; CPBHM; PPP1R90; HDAC6 |
Positive Sample: | HeLa,Hep G2 |
Conjugate: | Unconjugated |
Cellular Localization: | Axon cytoplasm, Caveola, Centrosome, Ciliary basal body, Cytoplasm, Cytosol, Histone deacetylase complex, Multivesicular body, Nucleoplasm, Nucleus, Perinuclear region of cytoplasm |
Calculated MW: | 131kDa |
Observed MW: | 160kDa |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Purification Method: | Affinity purification |
Gene ID: | 10013 |
Clone Number: | ARC0805 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |