The GSTK1 Monoclonal Antibody (CAB9667) is a valuable tool for researchers studying glutathione S-transferase kappa 1 (GSTK1), an enzyme involved in detoxification processes within cells. This antibody, produced in mice, demonstrates high specificity and sensitivity for detecting GSTK1 in various biological samples, particularly in Western blotting applications. By targeting the GSTK1 protein, researchers can accurately measure its levels in different cell types, allowing for detailed analysis in fields such as toxicology and cancer research.
GSTK1 is known for its role in protecting cells from oxidative stress and harmful toxins by facilitating the conjugation of glutathione to electrophilic compounds. Dysregulation of GSTK1 has been implicated in various diseases, making it a promising target for therapeutic interventions in conditions such as cancer, neurodegenerative disorders, and drug resistance. By investigating the function of GSTK1, researchers can gain insights into its potential as a biomarker or therapeutic target for disease management.
Product Name:
GSTK1 Rabbit Monoclonal Antibody
SKU:
CAB9667
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human GSTK1 (Q9Y2Q3).
This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
373156
Clone Number:
ARC1689
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GSTK1 Rabbit mAb (CAB9667) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
