The GSC Polyclonal Antibody (CAB19817) is a valuable tool for researchers studying GSC, a transcriptional repressor involved in the Hedgehog signaling pathway and implicated in the development of various cancers, including glioblastoma. Raised in rabbits, this antibody is highly specific and reacts with human samples, making it ideal for use in Western blot applications for protein detection and analysis.GSC, a critical regulator of stem cell maintenance and differentiation, plays a key role in various cellular processes, including embryonic development and tissue regeneration.
Dysregulation of GSC has been linked to tumorigenesis and cancer progression, highlighting its potential as a therapeutic target for cancer treatment and intervention.With its high reactivity and specificity, the GSC Polyclonal Antibody is a valuable tool for researchers investigating the molecular mechanisms underlying cancer development and progression. By enabling the detection and analysis of GSC expression in various cell types, this antibody contributes to the advancement of knowledge in cancer biology and the development of targeted therapies for cancer patients.
Product Name:
GSC Rabbit Monoclonal Antibody
SKU:
CAB19817
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GSC (P56915).
This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis.
Purification Method:
Affinity purification
Gene ID:
145258
Clone Number:
ARC2343
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GSC Rabbit mAb (CAB19817) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
