The Anti-GRIK2 Antibody (CAB9722) is a valuable tool for researchers studying the GRIK2 protein, which is a member of the kainate family of glutamate receptors. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.GRIK2 plays a crucial role in synaptic transmission and plasticity in the central nervous system, making it a key target for research into neurological disorders such as epilepsy, Alzheimer's disease, and schizophrenia.
By detecting and analyzing GRIK2 expression in different cell types, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic strategies.Overall, the Anti-GRIK2 Antibody (CAB9722) is a valuable tool for researchers interested in understanding the role of GRIK2 in brain function and neurological diseases. Its high reactivity and specificity make it an essential component of any study involving the GRIK2 protein.
Product Name:
GRIK2 Rabbit Monoclonal Antibody
SKU:
CAB9722
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human GRIK2 (Q13002).
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability.
Purification Method:
Affinity purification
Gene ID:
2898
Clone Number:
ARC1718
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse brain, using GRIK2 Rabbit mAb (CAB9722) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
