The GPRC5B Monoclonal Antibody (CAB20946) is a valuable tool for researchers studying GPRC5B, a G-protein coupled receptor implicated in various cellular processes, including cell growth and differentiation. This antibody, generated in mice, is highly specific for human GPRC5B and has been validated for use in immunohistochemistry applications. By targeting the GPRC5B protein, this antibody allows for the detection and analysis of GPRC5B expression in different tissues and cell types, making it an essential tool for investigations in cell biology and cancer research.GPRC5B, also known as retinoic acid-inducible protein 3 (RAI3), is involved in retinoic acid signaling pathways and has been linked to the development and progression of certain types of cancer.
Understanding the role of GPRC5B in these processes is critical for developing targeted therapies and biomarkers for cancer diagnosis and treatment. The GPRC5B Monoclonal Antibody provides researchers with a powerful tool to explore the function and regulation of GPRC5B in various biological contexts, paving the way for new insights into its potential as a therapeutic target.
Product Name:
GPRC5B Monoclonal Antibody
SKU:
CAB20946
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 304-403 of human GPRC5B (NP_057319.1).
This gene encodes a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The encoded protein may modulate insulin secretion and increased protein expression is associated with type 2 diabetes. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
51704
Clone Number:
ARC2932
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GPRC5B antibody (CAB20946) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
