The GPR77 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0308) is a powerful tool for researchers studying GPR77, a G protein-coupled receptor involved in various physiological processes, including immune response and inflammation. This antibody, produced in rabbits, exhibits high specificity and sensitivity when detecting GPR77 in human samples, making it an excellent choice for Western blot applications.GPR77, also known as LPAR5, is a key player in the regulation of immune cell migration and activation, making it an intriguing target for research in immunology and cancer biology. By binding to the GPR77 protein, this antibody enables precise detection and analysis of GPR77 expression in different cell types, providing valuable insights into its role in disease pathology.
With its ability to aid in the investigation of GPR77 function and signaling pathways, the GPR77 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0308) is an essential tool for researchers striving to unlock the therapeutic potential of targeting GPR77 in diseases such as cancer, autoimmune disorders, and inflammatory conditions. Explore the intricate workings of GPR77 with confidence using this reliable antibody in your research endeavors.
SKU:
HDAB0308
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC482
Synonyms:
C5L2; GPF77; GPR77
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
