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Anti-GPC3 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0254)

SKU:
HDAB0254
Product Type:
Rabbit Monoclonal Antibody
Antibody Type:
Monoclonal Antibody
Size:
100 μg
Reactivity:
Human
Host Species:
Rabbit
Antibody Isotype:
Rabbit/Human Fc chimeric IgG1
Clone:
DMC371
Synonyms:
DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1
$810
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Description

system_update_altDatasheet
SKU:HDAB0254
Size:100 µg
Clonality:Monoclonal
Clone:DMC371
Synonyms:DGSX; GTR2-2; MXR7; OCI-5; SDYS; SGB; SGBS; SGBS1
Applications:Flow Cyt
Recommended Dilution:Flow Cyt 1:100
Host Species:Rabbit
Isotype:Rabbit/Human Fc chimeric IgG1
Reactivity:Human
Purification Method:Purified from cell culture supernatant by affinity chromatography
Formulation:Powder
Buffer:1XPBS
Storage:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:Research use only
Background:Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] References： Fu Ying,Urban Daniel J,Nani Roger R et al. Glypican-3-Specific Antibody Drug Conjugates Targeting Hepatocellular Carcinoma.[J] .Hepatology, 2019, 70: 563-576. Zhang Yi-Fan,Ho Mitchell,Humanization of high-affinity antibodies targeting glypican-3 in hepatocellular carcinoma.

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