The Anti-GPAT4 Antibody (CAB20804) is a crucial tool for researchers studying GPAT4, an enzyme involved in the glycerolipid biosynthesis pathway. This antibody, produced through immunization of rabbits, exhibits high specificity and reactivity towards GPAT4 in human samples, making it suitable for Western blot applications. By binding to GPAT4, this antibody enables accurate detection and analysis in various cell types, facilitating investigations in lipid metabolism, energy storage, and related pathways.GPAT4, also known as glycerol-3-phosphate acyltransferase 4, plays a key role in the synthesis of glycerolipids, essential components of cell membranes and storage lipids.
Dysfunction of GPAT4 has been implicated in metabolic disorders, such as obesity and insulin resistance, highlighting its significance in lipid homeostasis. Research on GPAT4 can provide insights into lipid-related diseases and potential therapeutic targets for metabolic conditions.By utilizing the Anti-GPAT4 Antibody (CAB20804), researchers can delve deeper into the functions and regulations of GPAT4, advancing our understanding of lipid metabolism and metabolic diseases. This antibody is a valuable tool for studies in biochemistry, cell biology, and metabolic research, offering new possibilities for exploring the intricate mechanisms of lipid synthesis and metabolism.
Product Name:
GPAT4 Polyclonal Antibody
SKU:
CAB20804
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 205-456 of human GPAT4 (NP_848934.1).
Lysophosphatidic acid acyltransferases (EC 2.3.1.51) catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA). LPA and PA are involved in signal transduction and lipid biosynthesis.
Purification Method:
Affinity purification
Gene ID:
137964
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse pancreas, using GPAT4 Rabbit pAb (CAB20804) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
