Based on the information from the URL provided, here is a product description:The Anti-GPA33 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0320) is a powerful tool for research purposes involving GPA33, a cell surface glycoprotein that is specifically expressed in colon and rectal cancer cells. This antibody, derived from rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including immunohistochemistry and flow cytometry.GPA33 is a promising target for cancer research due to its unique expression pattern in colorectal cancer, making it an attractive candidate for targeted therapies and diagnostic tools.
Understanding the role of GPA33 in tumor growth and progression is crucial for developing effective treatment strategies for patients with this type of cancer.By using the Anti-GPA33 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0320), researchers can accurately detect and analyze GPA33 expression in cancer cells, providing valuable insights into the mechanisms underlying colorectal cancer development and progression. This antibody is a valuable asset for studies in oncology and has the potential to contribute to the development of novel therapeutic approaches for colorectal cancer patients.
SKU:
HDAB0320
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC497
Synonyms:
A33
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. [provided by RefSeq, Jul 2008]
