The Anti-GP6 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0271) offered by Assay Genie is a cutting-edge tool for researchers studying the glycoprotein VI (GP6) molecule. GP6 is known to play a key role in platelet activation and aggregation, making it a crucial target for studies in cardiovascular disease, thrombosis, and hemostasis.This antibody, developed using advanced chimeric recombinant rabbit monoclonal technology, provides high specificity and sensitivity in detecting GP6 in various sample types. It is validated for use in multiple applications, including Western blotting and immunohistochemistry, enabling accurate and reliable results in research studies.
By targeting GP6, researchers can gain valuable insights into the mechanisms underlying platelet function and clot formation, paving the way for the development of novel therapeutics targeting GP6-related pathways in cardiovascular and thrombotic disorders. With its superior performance and versatility, the Anti-GP6 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0271) is an essential tool for advancing research in this critical area of study.
SKU:
HDAB0271
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC427
Synonyms:
BDPLT11; GPIV; GPVI
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
