The Glycerol Kinase (GK) Polyclonal Antibody (CAB19221) is a valuable tool for researchers studying Glycerol Kinase, an enzyme involved in glycerol metabolism. This antibody, produced in rabbits, has high specificity for human samples and is suitable for Western blot applications. By binding to the GK protein, this antibody allows for the detection and analysis of GK in various cell types, making it ideal for investigations in biochemistry and metabolic research.
Glycerol Kinase is a key enzyme in glycerol utilization pathways, playing a crucial role in lipid metabolism and energy production. Dysregulation of GK activity has been implicated in metabolic disorders such as diabetes and obesity, making it a potential therapeutic target for these conditions. Understanding the function and regulation of GK is essential for developing interventions that target glycerol metabolism and its associated diseases.
Product Name:
Glycerol kinase (GK) Rabbit Monoclonal Antibody
SKU:
CAB19221
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 450-559 of human Glycerol kinase (GK) (P32189).
The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2710
Clone Number:
ARC2376
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Glycerol kinase (GK) Rabbit mAb (CAB19221) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
