Gli3 Rabbit Monoclonal Antibody (CAB3300)
- SKU:
- CAB3300
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ACLS
- GCPS
- GLI3-190
- GLI3FL
- PAP-A
- PAPA
- PAPA1
- PAPB
- PHS
- PPDIV
Frequently bought together:
Description
Product Name: | Gli3 Rabbit Monoclonal Antibody |
SKU: | CAB3300 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1301-1580 of human Gli3 (P10071). |
Sequence: | PNES AGSM VNGM QNQD PVGQ GYLA HQLL GDSM QHPG AGRP GQQM LGQI SATS HINI YQGP ESCL PGAH GMGS QPSS LAVV RGYQ PCAS FGGS RRQA MPRD SLAL QSGQ LSDT SQTC RVNG IKME MKGQ PHPL CSNL QNYS GQFY DQTV GFSQ QDTK AGSF SISD ASCL LQGT SAKN SELL SPGA NQVT STVD SLDS HDLE GVQI DFDA IIDD GDHS SLMS GALS PSII QNLS HSSS RLTT PRAS LPFP ALSM STTN MAIG DMSS LLTS LAEE SKFL AVMQ |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | PHS; ACLS; GCPS; PAPA; PAPB; PAP-A; PAPA1; PPDIV; GLI3FL; GLI3-190; Gli3 |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Axoneme, Ciliary base, Ciliary tip, Cilium, Cytoplasm, Cytosol, GLI-SUFU complex, Nuclear speck, Nucleolus, Nucleoplasm, Nucleus |
Calculated MW: | 170kDa |
Observed MW: | 190kDa |
This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.
Purification Method: | Affinity purification |
Gene ID: | 2737 |
Clone Number: | ARC1941 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |