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GJA8 Rabbit Polyclonal Antibody (CAB19312)

SKU:
CAB19312
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CAE
CAE1
CTRCT1
CX50
CZP1
MP70
GJA8
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:GJA8 Rabbit Polyclonal Antibody
SKU:CAB19312
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 234-433 of human GJA8 (NP_005258.2).
Sequence:SALK RPVE QPLG EIPE KSLH SIAV SSIQ KAKG YQLL EEEK IVSH YFPL TEVG MVET SPLP AKPF NQFE EKIS TGPL GDLS RGYQ ETLP SYAQ VGAQ EVEG EGPP AEEG AEPE VGEK KEEA ERLT TEEQ EKVA VPEG EKVE TPGV DKEG EKEE PQSE KVSK QGLP AEKT PSLC PELT TDDA RPLS RLSK ASSR ARSD DLTV
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:CAE; CAE1; CX50; CZP1; MP70; CTRCT1; GJA8
Positive Sample:Raji
Conjugate:Unconjugated
Cellular Localization:connexin complex, plasma membrane
Calculated MW:48kDa
Observed MW:48kDa

This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.

Purification Method:Affinity purification
Gene ID:2703
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Raji cells, using GJA8 Rabbit pAb (CAB19312) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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