The GIMAP1 Polyclonal Antibody (CAB20356) is a key tool for researchers studying the role of GIMAP1, a protein involved in immune cell function and regulation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By targeting the GIMAP1 protein, this antibody allows for accurate detection and analysis in various cell types, making it an essential component in immunology and cancer research studies.
GIMAP1, also known as GTPase of immunity-associated protein 1, plays a crucial role in immune cell survival and function. Its involvement in immune system modulation makes it a promising target for research on diseases such as cancer, autoimmune disorders, and inflammatory conditions. Understanding the mechanisms of GIMAP1 can provide valuable insights for the development of therapies aimed at modulating immune responses in these disease contexts.
Product Name:
GIMAP1 Rabbit pAb
Product Code:
CAB20356
Size:
50uL, 100uL
Synonyms:
IAN2, IMAP1, HIMAP1, IMAP38
Applications:
WB
Reactivity:
Human, Mouse, Rat
Host Species:
Rabbit
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 140-280 of human GIMAP1 (NP_570115.1).
Applications:
WB
Recommended Dilutions:
WB 1:500 - 1:2000
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 140-280 of human GIMAP1 (NP_570115.1).
Purification Method:
Affinity purification
Storage:
Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:
IgG
Sequence:
Email for sequence
Gene ID:
170575
Uniprot:
Q8WWP7
Calculated MW:
34kDa
Observed MW:
Refer to figures
Background:
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene is thought to be involved in the differentiation of T helper (Th) cells of the Th1 lineage, and the related mouse gene has been shown to be critical for the development of mature B and T lymphocytes. Read-through transcription exists between this gene and the downstream GIMAP5 (GTPase, IMAP family member 5) gene.
