The Gid Antibody (CAB20578) is a high-quality polyclonal antibody specifically designed for research involving Gid, a protein involved in the regulation of cell growth and differentiation. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting and immunohistochemistry.Gid plays a crucial role in the ubiquitin-proteasome pathway, where it regulates the degradation of specific proteins involved in cell cycle progression and signal transduction. Dysregulation of Gid has been implicated in various diseases, including cancer, making it a promising target for drug development and therapeutic interventions.
By utilizing the Gid Antibody (CAB20578), researchers can effectively detect and analyze the expression of Gid in different cell types, providing valuable insights into its function and potential as a therapeutic target. This antibody is an essential tool for studies in cancer biology, cell signaling, and drug discovery, contributing to advancements in understanding disease mechanisms and developing targeted therapies.
Product Name:
GID Rabbit Polyclonal Antibody
SKU:
CAB20578
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Oryza sativa
Immunogen:
Recombinant protein of Oryza sativa GID.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
gid1; P0040B10.6; OJ1657_H11.10; GID
Positive Sample:
leaves,stems,spikes,milk grains
Conjugate:
Unconjugated
Cellular Localization:
cytoplasm, nucleus
Calculated MW:
39kDa
Observed MW:
50kDa
Functions as soluble gibberellin (GA) receptor. GA is an essential hormone that regulates growth and development in plants. Binds with high affinity the biologically active GAs such as GA1, GA3 and GA4, but has low or no affinity for the biologically inactive GAs. Upon GA-binding, it interacts with the DELLA protein SLR1, a repressor of GA signaling. This leads to SLR1 degradation by the proteasome, allowing the GA signaling pathway.
Purification Method:
Affinity purification
Gene ID:
4338764
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various tissues from the japonica rice (Oryza sativa L.) variety Zhonghua 11, using GID Rabbit pAb (CAB20578) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 120s.
