The Anti-GH1 Antibody (CAB7675) is a valuable tool for researchers studying GH1, a growth hormone protein essential for regulating growth, metabolism, and various physiological processes in the body. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the GH1 protein, this antibody enables accurate detection and analysis in a range of cell types, making it an ideal choice for investigations in endocrinology and growth-related studies.
GH1, also known as somatotropin, plays a crucial role in growth and development by stimulating the production of insulin-like growth factor (IGF-1) and promoting cell growth and division. Its involvement in metabolic processes and tissue repair underscores its importance in understanding growth disorders, metabolic diseases, and other conditions related to hormonal imbalance. Research on GH1 is key to unveiling insights into growth regulation and developing therapies for growth-related disorders and metabolic conditions.
Product Name:
GH1 Rabbit Polyclonal Antibody
SKU:
CAB7675
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human GH1 (NP_000506.2).
Sequence:
ELLR ISLL LIQS WLEP VQFL RSVF ANSL VYGA SDSN VYDL LKDL EEGI QTLM GRLE DGSP RTGQ IFKQ TYSK FDTN SHND DALL KNYG LLYC FRKD MDKV E
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
Purification Method:
Affinity purification
Gene ID:
2688
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse liver using GH1 Rabbit pAb(CAB7675) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time:10s.
