The Anti-GFAP (7-66) Recombinant Monoclonal Antibody (HDAB0205) is a highly specific antibody designed for research involving Glial Fibrillary Acidic Protein (GFAP), a protein commonly used as a marker for astrocytes in the central nervous system. This antibody, derived from recombinant monoclonal technology, offers high sensitivity and specificity for detecting GFAP in various cell types and tissues.GFAP is essential for the structural integrity of astrocytes and is involved in various cellular functions, including cytoskeletal organization and response to injury and disease. Abnormalities in GFAP expression have been linked to neurological disorders such as Alzheimer's disease, multiple sclerosis, and gliomas.
As such, studying the expression and localization of GFAP using this antibody can provide valuable insights into the pathophysiology of these conditions.With its high reactivity and validated performance in immunohistochemistry and other applications, the Anti-GFAP (7-66) Recombinant Monoclonal Antibody (HDAB0205) is an essential tool for researchers in neuroscience, pathology, and related fields aiming to investigate GFAP expression patterns and functions in health and disease.
SKU:
HDAB0205
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM215
Synonyms:
ALXDRD
Applications:
ELISA
Recommended Dilution:
ELISA 1:5000-10000
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
