Gemin 2 Rabbit Monoclonal Antibody (CAB19254)
- SKU:
- CAB19254
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GEMIN2
- SIP1
- SIP1-delta
- gem-associated protein 2
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Gemin 2 Rabbit Monoclonal Antibody |
SKU: | CAB19254 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Gemin 2 (O14893). |
Sequence: | MRRA ELAG LKTM AWVP AESA VEEL MPRL LPVE PCDL TEGF DPSV PPRT PQEY LRRV QIEA AQCP DVVV AQID PKKL KRKQ SVNI SLSG CQPA PEGY SPTL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | SIP1; SIP1-delta; Gemin 2 |
Positive Sample: | U-2 OS,HeLa,MCF7,Mouse testis,Mouse thymus,Rat testis,Rat pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, gem. |
Calculated MW: | 32kDa |
Observed MW: | 32kDa |
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
Purification Method: | Affinity purification |
Gene ID: | 8487 |
Clone Number: | ARC2419 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |