The Anti-Gelsolin Antibody (CAB2612) is a valuable tool for researchers studying gelsolin, a protein involved in actin filament assembly and disassembly. This polyclonal antibody is raised in rabbits and exhibits high reactivity with human samples, making it ideal for use in various research applications, including Western blotting.Gelsolin is known to play a role in cell motility, cytokinesis, and apoptosis, making it a key player in cellular processes. By targeting gelsolin with this antibody, researchers can investigate its function and expression levels in different cell types and tissues, providing valuable insights into its role in normal physiology and disease states.
Furthermore, gelsolin has been implicated in various diseases, including cancer, Alzheimer's disease, and cardiovascular disorders. Understanding the mechanisms by which gelsolin contributes to these conditions can lead to the development of novel therapeutic strategies for treating and managing these diseases.Overall, the Anti-Gelsolin Antibody (CAB2612) is a reliable tool for researchers looking to delve deeper into the biology of gelsolin and its implications in health and disease.
Product Name:
Gelsolin Rabbit Monoclonal Antibody
SKU:
CAB2612
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human Gelsolin (NP_000168.1).
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2934
Clone Number:
ARC1924
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Gelsolin Rabbit mAb (CAB2612) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
