GALNT4 Rabbit Polyclonal Antibody (CAB4243)
- SKU:
- CAB4243
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GALNT4
- GALNAC-T4
- GALNACT4
Description
Product Name: | GALNT4 Rabbit Polyclonal Antibody |
SKU: | CAB4243 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-133 of human GALNT4 (NP_003765.2). |
Sequence: | RARE LGSR RLSD LQKN TEDL SRPL YKKP PADS RALG EWGK ASKL QLNE DELK QQEE LIER YAIN IYLS DRIS LHRH IEDK RMYE CKSQ KFNY RT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | GALNACT4; GALNAC-T4; GALNT4 |
Positive Sample: | HeLa,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Golgi apparatus membrane, Single-pass type II membrane protein. |
Calculated MW: | 67kDa |
Observed MW: | 67kDa |
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon. Fusion transcripts, which combine part of this gene with the 5' exons of the neighboring POC1B (POC1 centriolar protein homolog B) gene, also exist.
Purification Method: | Affinity purification |
Gene ID: | 8693 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |