The Anti-FZD10 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0313) is a powerful tool for researchers studying the FZD10 protein, a member of the Frizzled family involved in Wnt signaling pathways. This antibody, developed using cutting-edge technology, exhibits high affinity and specificity for FZD10 and has been validated for use in various applications including Western blot, immunohistochemistry, and flow cytometry.FZD10 plays a crucial role in cell signaling processes that regulate cell proliferation, differentiation, and migration, making it a key target for studies in developmental biology, oncology, and regenerative medicine.
By targeting FZD10 with this antibody, researchers can gain valuable insights into the function and regulation of this important protein, paving the way for potential therapeutic interventions in various disease contexts.Overall, the Anti-FZD10 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0313) is a valuable tool for researchers looking to explore the role of FZD10 in different biological processes and disease conditions, ultimately contributing to the advancement of scientific knowledge and the development of targeted therapies.
SKU:
HDAB0313
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC487
Synonyms:
CD350; FZ-10; Fz10; FzE7; hFz10
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq, Jul 2008]