The FXYD3 Polyclonal Antibody (CAB20301) is a valuable tool for research involving the FXYD3 protein, a member of the FXYD family of ion transport regulators. This antibody, generated in rabbits, has high specificity for human samples and is validated for use in Western blot applications. By binding to the FXYD3 protein, this antibody enables accurate detection and analysis in various cell types, making it an excellent choice for studies in physiology, cell biology, and disease research.FXYD3 is known to regulate the function of Na,K-ATPase, an essential ion pump involved in maintaining cell volume and electrochemical gradients.
Dysregulation of FXYD3 has been linked to various diseases, including cancer and cardiovascular disorders. Research into the role of FXYD3 is crucial for understanding its impact on cell physiology and identifying potential therapeutic targets for these conditions.This antibody provides researchers with a reliable tool for studying the function and expression of FXYD3 in different biological systems, paving the way for advancements in the fields of ion transport regulation and disease treatment.
Product Name:
FXYD3 Polyclonal Antibody
SKU:
CAB20301
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human FXYD3 (NP_005962.1).
This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
5349
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human colon using FXYD3 Rabbit pAb (CAB20301) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
