The FUT11 Polyclonal Antibody (CAB20351) is a valuable tool for researchers studying the FUT11 protein, an enzyme involved in the glycosylation of proteins and the biosynthesis of Lewis antigens. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in Western blot applications. By binding to the FUT11 protein, this antibody allows for the precise detection and analysis of FUT11 expression in a variety of cell types, making it an essential component in studies focusing on glycobiology and cancer research.
FUT11 is a key player in the regulation of glycosylation patterns on cell surface molecules, influencing various cellular processes such as cell adhesion, signaling, and immune responses. Dysregulation of FUT11 expression has been implicated in the development and progression of cancer, making it a promising target for therapeutic interventions. By investigating the role of FUT11 in glycosylation pathways, researchers can gain insights into the mechanisms underlying tumorigenesis and potentially identify novel strategies for cancer treatment.
Product Name:
FUT11 Polyclonal Antibody
SKU:
CAB20351
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-205 of human FUT11 (NP_775811.2).
Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. Predicted to be located in Golgi cisterna membrane. Predicted to be integral component of membrane.
Purification Method:
Affinity purification
Gene ID:
170384
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of 293T, using FUT11 Rabbit pAb (CAB20351) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
