The Anti-FOXL2 Antibody (CAB3597) is a highly specific and sensitive tool for research involving the FOXL2 protein, a key transcription factor involved in ovarian development and function. This polyclonal antibody, raised in rabbits, is suitable for use in various applications such as immunofluorescence, immunohistochemistry, and Western blotting.FOXL2 is crucial for the development and maintenance of ovarian tissue and plays a vital role in the regulation of genes involved in ovarian function. Mutations in the FOXL2 gene have been linked to disorders such as blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES), as well as ovarian failure.
This antibody is ideal for studying the expression and localization of FOXL2 in different cell types and tissues, providing valuable insights into its function and potential implications in disease.By utilizing the Anti-FOXL2 Antibody (CAB3597), researchers can further explore the role of FOXL2 in ovarian biology and pathology, potentially leading to new therapeutic targets and strategies for treating disorders related to ovarian function and development. Its high specificity and sensitivity make it a reliable tool for advancing research in the fields of reproductive biology, developmental genetics, and endocrinology.
Product Name:
FOXL2 Rabbit Monoclonal Antibody
SKU:
CAB3597
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FOXL2 (P58012).
This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Expansion of a polyalanine repeat region and other mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3.
Purification Method:
Affinity purification
Gene ID:
668
Clone Number:
ARC2055
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FOXL2 Rabbit mAb (CAB3597) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
