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Anti-FOLR2 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0258)

SKU:
HDAB0258
Product Type:
Rabbit Monoclonal Antibody
Antibody Type:
Monoclonal Antibody
Size:
100 μg
Reactivity:
Human
Host Species:
Rabbit
Antibody Isotype:
Rabbit/Human Fc chimeric IgG1
Clone:
DMC390
Synonyms:
BETA-HFR, FBP, FBP/PL-1, FOLR1, FR-BETA, FR-P3, FRbeta
€675
Frequently bought together:

Description

system_update_altDatasheet
SKU:HDAB0258
Size:100 µg
Clonality:Monoclonal
Clone:DMC390
Synonyms:BETA-HFR; FBP; FBP/PL-1; FOLR1; FR-BETA; FR-P3; FRbeta
Applications:Flow Cyt
Recommended Dilution:Flow Cyt 1:100
Host Species:Rabbit
Isotype:Rabbit/Human Fc chimeric IgG1
Reactivity:Human
Purification Method:Purified from cell culture supernatant by affinity chromatography
Formulation:Powder
Buffer:1XPBS
Storage:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:Research use only
Background:The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.

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