The Anti-FOLR2 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0258) is a cutting-edge research tool designed for studying FOLR2, a cell surface receptor involved in folate metabolism and cancer progression. This antibody, carefully developed using advanced technology, demonstrates high specificity and sensitivity in detecting FOLR2 in human samples.FOLR2, also known as folate receptor beta, plays a crucial role in folate uptake and intracellular transport, making it a potential target for cancer therapy and diagnosis. Its overexpression in many cancer types makes it an attractive biomarker for identifying and monitoring disease progression. The Anti-FOLR2 antibody enables researchers to explore the functions of FOLR2 in various cell types and tissues, facilitating studies in oncology, molecular biology, and drug development.
This antibody is validated for use in Western blot and immunohistochemistry applications, providing researchers with a reliable tool for investigating FOLR2 expression and localization. By understanding the role of FOLR2 in cancer biology, researchers can uncover new therapeutic targets and strategies for improving cancer treatment outcomes. Dive into the world of FOLR2 research with the Anti-FOLR2 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0258) and unlock new possibilities in cancer research and precision medicine.
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.
