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Fibrinogen alpha chain (FGA) Rabbit Monoclonal Antibody (CAB19658)

SKU:
CAB19658
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
Fib2
Research Area:
Immunology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Fibrinogen alpha chain (FGA) Rabbit Monoclonal Antibody
SKU:CAB19658
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 700-800 of human Fibrinogen alpha chain (FGA) (FGA) (P02671).
Sequence:NDEG EGEF WLGN DYLH LLTQ RGSV LRVE LEDW AGNE AYAE YHFR VGSE AEGY ALQV SSYE GTAG DALI EGSV EEGA EYTS HNNM QFST FDRD ADQW EENC A
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:Fib2; Fibrinogen alpha chain (FGA)
Positive Sample:Rat liver
Conjugate:Unconjugated
Cellular Localization:blood microparticle, cell surface, endoplasmic reticulum, endoplasmic reticulum lumen, external side of plasma membrane, extracellular exosome, extracellular region, extracellular space, extracellular vesicle, fibrinogen complex, plasma membrane
Calculated MW:95kDa
Observed MW:95kDa

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing.

Purification Method:Affinity purification
Gene ID:2243
Clone Number:ARC2227
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Fibrinogen alpha chain (FGA) (FGA) Rabbit mAb (CAB19658) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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