The Fibrinogen Alpha Chain (FGA) Antibody (CAB19658) is a valuable tool for researchers studying fibrinogen, a key protein involved in blood clot formation. This antibody is raised in rabbits and has been validated for use in various applications, including Western blot and immunohistochemistry. It specifically targets the FGA protein, allowing for precise detection and analysis in human samples.Fibrinogen is essential for hemostasis and wound healing, making it a crucial target for studies in cardiovascular disease, thrombosis, and inflammation.
The FGA Antibody offers researchers a reliable means of investigating the role of fibrinogen in these processes, providing insights into potential therapeutic strategies for conditions related to abnormal clotting and inflammation.By utilizing the FGA Antibody, researchers can further explore the complex mechanisms involving fibrinogen and its implications for various health conditions. Its high reactivity and specificity make it an excellent tool for advancing our understanding of fibrinogen biology and its relevance to human health.
This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing.
Purification Method:
Affinity purification
Gene ID:
2243
Clone Number:
ARC2227
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Fibrinogen alpha chain (FGA) (FGA) Rabbit mAb (CAB19658) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
