The Fetuin A/AHSG Monoclonal Antibody (CAB19264) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and is validated for use in Western blot applications.FETUIN-A, also known as alpha-2-HS-glycoprotein, is recognized for its role in inhibiting insulin receptor autophosphorylation, making it a key player in metabolic regulation and insulin sensitivity. Additionally, FETUIN-A has been implicated in the pathogenesis of conditions like obesity, diabetes, and cardiovascular disease, making it a promising target for therapeutic interventions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
Fetuin A/AHSG Monoclonal Antibody
SKU:
CAB19264
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC2433
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
AHS, A2HS, HSGA, APMR1, FETUA, Fetuin A/AHSG
Positive Sample:
Human plasma
Cellular Localization:
Secreted.
Calculated MW:
39kDa
Observed MW:
50kDa
The protein encoded by this gene is a negatively-charged serum glycoprotein that is synthesized by hepatocytes. The encoded protein consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several processes, including endocytosis, brain development, and the formation of bone tissue. Defects in this gene are a cause of susceptibility to leanness.
Purification Method
Affinity purification
Gene ID
197
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Human plasma, using Fetuin A/AHSG Rabbit mAb (CAB19264) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.