The FAM50B Polyclonal Antibody (CAB20245) is a valuable tool for researchers studying the FAM50B protein, a key regulator of gene expression and chromatin organization. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the FAM50B protein, this antibody enables precise detection and analysis of FAM50B expression in various cell types, making it an essential component for studies in molecular biology and genetics.FAM50B, also known as a component of the SET complex, plays a pivotal role in modulating gene transcription and chromatin remodeling processes.
Its involvement in these fundamental cellular functions underscores its importance in various biological processes, including cell differentiation, development, and disease progression. Research into the function of FAM50B can provide valuable insights into potential therapeutic targets for conditions such as cancer, neurodegenerative diseases, and developmental disorders. By elucidating the mechanisms by which FAM50B influences gene expression, researchers can uncover novel strategies for treating a wide range of health conditions.
Product Name:
Fam50b Polyclonal Antibody
SKU:
CAB20245
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 70-150 of mouse Fam50b (NP_620085.2).
Predicted to be involved in chromatin organization. Predicted to be located in intercellular bridge; midbody; and nucleoplasm. Predicted to be active in nucleus. Is expressed in primary spermatocyte; seminiferous tubule; and spermatid. Orthologous to human FAM50B (family with sequence similarity 50 member B).
Purification Method:
Affinity purification
Gene ID:
108161
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse testis, using Fam50b Rabbit pAb (CAB20245) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.