The Anti-Exportin-2 (XPO2) Antibody (CAB1041) is an essential tool for researchers investigating Exportin-2 (XPO2), a nuclear transporter protein involved in the export of cellular proteins. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.Exportin-2 plays a crucial role in the regulation of cellular processes by controlling the transport of proteins out of the nucleus. Studies have shown that dysregulation of XPO2 can lead to various diseases, including cancer and neurodegenerative disorders.
By targeting XPO2 with this antibody, researchers can gain valuable insights into its function and potential therapeutic targets.The Anti-Exportin-2 (XPO2) Antibody (CAB1041) is a valuable tool for researchers in the fields of molecular biology, cell biology, and cancer research. Its ability to specifically detect XPO2 in various cell types makes it an ideal choice for studies aimed at understanding the role of protein transport in cellular function and disease development.
Product Name:
Exportin 2 (XPO2) Rabbit Monoclonal Antibody
SKU:
CAB1041
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 872-971 of human Exportin 2 (XPO2) (P55060).
CSE1L (Chromosome Segregation 1-Like) is located on 20q13.13, and encodes a 971-amino-acid protein. It associates with microtubules and mitotic spindles, and is also considered to have a role in tumor progression. The CSE1L protein includes a nuclear localization signal allowing for transport into the nucleus via the importin-alpha/beta heterodimer. In addition, CSE1L plays roles in cell proliferation and apoptosis.
Purification Method:
Affinity purification
Gene ID:
1434
Clone Number:
ARC1856
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Exportin 2 (XPO2) Rabbit mAb (CAB1041) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
