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Exportin 2 (XPO2) Rabbit Monoclonal Antibody (CAB1041)

SKU:
CAB1041
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CAS
CSE1
XPO2
Research Area:
Cell Biology
$167 - $503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Exportin 2 (XPO2) Rabbit Monoclonal Antibody
SKU:CAB1041
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 872-971 of human Exportin 2 (XPO2) (P55060).
Sequence:LIGL FELP EDDT IPDE EHFI DIED TPGY QTAF SQLA FAGK KEHD PVGQ MVNN PKIH LAQS LHKL STAC PGRV PSMV STSL NAEA LQYL QGYL QAAS VTLL
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:CAS; CSE1; XPO2; Exportin 2 (XPO2)
Positive Sample:HeLa,293T,Jurkat,Mouse testis,Mouse thymus
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus
Calculated MW:110kDa
Observed MW:105kDa

CSE1L (Chromosome Segregation 1-Like) is located on 20q13.13, and encodes a 971-amino-acid protein. It associates with microtubules and mitotic spindles, and is also considered to have a role in tumor progression. The CSE1L protein includes a nuclear localization signal allowing for transport into the nucleus via the importin-alpha/beta heterodimer. In addition, CSE1L plays roles in cell proliferation and apoptosis.

Purification Method:Affinity purification
Gene ID:1434
Clone Number:ARC1856
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using Exportin 2 (XPO2) Rabbit mAb (CAB1041) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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