The ERP29 Polyclonal Antibody (CAB19771) is a valuable tool for researchers studying ERP29, a protein involved in protein folding and quality control within the endoplasmic reticulum. The antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for use in Western blot and immunohistochemistry applications.ERP29 is a key player in maintaining cellular homeostasis and ensuring proper protein folding, particularly under conditions of stress. Dysregulation of ERP29 has been implicated in various diseases, including cancer and neurodegenerative disorders.
By targeting ERP29 with this antibody, researchers can investigate its function and potential as a therapeutic target in these disease contexts.This antibody offers researchers a reliable tool for detecting and quantifying ERP29 expression in different cell types and tissues, providing valuable insights into its role in various cellular processes. With its high specificity and validated performance, the ERP29 Polyclonal Antibody (CAB19771) is a valuable asset for researchers exploring the mechanisms of protein quality control and their implications in disease pathogenesis.
Product Name:
ERp29 Rabbit Monoclonal Antibody
SKU:
CAB19771
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human ERp29 (P30040).
This gene encodes a protein which localizes to the lumen of the endoplasmic reticulum (ER). It is a member of the protein disulfide isomerase (PDI) protein family but lacks an active thioredoxin motif, suggesting that this protein does not function as a disulfide isomerase. The canonical protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
10961
Clone Number:
ARC2295
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ERp29 Rabbit mAb (CAB19771) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
