The Anti-ERP19 Antibody (CAB9386) is a highly specific antibody designed for research involving ERP19, a protein involved in endoplasmic reticulum (ER) protein quality control. This polyclonal antibody, generated in rabbits, is suitable for detecting and analyzing ERP19 in human samples, making it a valuable tool for studies in cell biology, protein folding, and ER stress response.ERP19 is a key player in maintaining ER homeostasis by assisting in protein folding and quality control processes. Dysregulation of ERP19 expression or function has been linked to ER stress-related diseases such as neurodegenerative disorders, diabetes, and cardiovascular diseases.
By targeting ERP19 with this antibody, researchers can gain insights into its role in ER function and explore potential therapeutic strategies for ER stress-related conditions.Overall, the Anti-ERP19 Antibody (CAB9386) offers a reliable and specific tool for investigating ERP19 biology and its implications in various physiological and pathological processes. Its versatility in detecting ERP19 in different experimental settings makes it an essential reagent for researchers interested in understanding ER protein quality control mechanisms.
Product Name:
ERp19 Monoclonal Antibody
SKU:
CAB9386
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ERp19 (NP_056997.1).
This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants.
Purification Method:
Affinity purification
Gene ID:
51060
Clone Number:
ARC2718
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using (CAB9386) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
