ERAB/HSD17B10 Rabbit Monoclonal Antibody (CAB0959)
- SKU:
- CAB0959
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- 17b-HSD10
- ABAD
- CAMR
- DUPXp11.22
- ERAB
- HADH2
- HCD2
- MHBD
- MRPP2
- MRX17
- MRX31
- MRXS10
- SCHAD
- SDR5C1
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | ERAB/HSD17B10 Rabbit Monoclonal Antibody |
SKU: | CAB0959 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 162-261 of human ERAB/HSD17B10 (Q99714). |
Sequence: | QVGQ AAYS ASKG GIVG MTLP IARD LAPI GIRV MTIA PGLF GTPL LTSL PEKV CNFL ASQV PFPS RLGD PAEY AHLV QAII ENPF LNGE VIRL DGAI RMQP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | ABAD; CAMR; ERAB; HCD2; MHBD; HADH2; MRPP2; MRX17; MRX31; SCHAD; MRXS10; SDR5C1; HSD10MD; 17b-HSD10; DUPXp11.22; ERAB/HSD17B10 |
Positive Sample: | 293T,HepG2,U-87MG,Mouse liver,Mouse kidney,Mouse heart,Rat liver,Rat kidney,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 27kDa |
Observed MW: | 26kDa |
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Purification Method: | Affinity purification |
Gene ID: | 3028 |
Clone Number: | ARC1852 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |