The Anti-EPHA4 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0298) is a cutting-edge tool for research involving EPHA4, a member of the ephrin receptor subfamily of protein-tyrosine kinases. This antibody, developed using innovative chimeric recombinant technology, offers high specificity and sensitivity for detecting EPHA4 in various cell types and tissues.EPHA4 plays a crucial role in regulating cell adhesion and migration, as well as neural development and synaptic plasticity. Dysregulation of EPHA4 has been implicated in various diseases, including cancer, neurodegenerative disorders, and developmental abnormalities.
The Anti-EPHA4 antibody is validated for use in applications such as Western blot, immunofluorescence, and immunohistochemistry, providing researchers with a powerful tool for studying the function and signaling pathways of EPHA4.With its high reactivity and reliability, the Anti-EPHA4 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0298) is an invaluable resource for investigations into the role of EPHA4 in health and disease. Whether studying neurobiology, oncology, or developmental biology, this antibody offers precision and accuracy for uncovering the intricacies of EPHA4 biology.
SKU:
HDAB0298
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC472
Synonyms:
EK8; HEK8; SEK; TYRO1
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
