The ENTPD5 Polyclonal Antibody (CAB19647) is developed for research involving ENTPD5, a key enzyme involved in nucleotide metabolism and cell signaling. This antibody, generated in rabbits, exhibits high reactivity towards human samples and is validated for use in various applications including Western blot and immunohistochemistry.ENTPD5, also known as CD39L4, is a critical player in regulating extracellular nucleotide levels and modulating purinergic signaling pathways. Its role in maintaining cellular homeostasis and responding to stress signals makes it a promising target for studying diseases such as cancer, cardiovascular disorders, and neurological conditions.
Understanding the function of ENTPD5 can provide valuable insights into these disease processes and potentially lead to the development of targeted therapies.Overall, the ENTPD5 Polyclonal Antibody is a valuable tool for researchers interested in exploring the biological functions and potential therapeutic applications of ENTPD5 in various disease contexts. Its high specificity and sensitivity make it an excellent choice for experiments aiming to elucidate the role of ENTPD5 in nucleotide metabolism and signaling pathways.
Product Name:
ENTPD5 Rabbit Monoclonal Antibody
SKU:
CAB19647
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human ENTPD5 (O75356).
endoplasmic reticulum, extracellular region, extracellular space
Calculated MW:
48kDa
Observed MW:
48kDa
The protein encoded by this gene is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases.
Purification Method:
Affinity purification
Gene ID:
957
Clone Number:
ARC2211
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ENTPD5 Rabbit mAb (CAB19647) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
