The anti-ENTPD5 Antibody (CAB19642) is a polyclonal antibody designed for research involving ENTPD5, a cell surface enzyme known for its role in nucleotide metabolism and stress response. The antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications including Western blot and immunofluorescence.ENTPD5, also known as ectonucleoside triphosphate diphosphohydrolase 5, is a multifunctional enzyme that plays a crucial role in regulating cellular nucleotide levels and maintaining cellular homeostasis. In particular, ENTPD5 is involved in the hydrolysis of extracellular nucleotides, which can impact various cellular processes such as cell proliferation, apoptosis, and immune responses.
Research into ENTPD5 is essential for understanding its role in diseases such as cancer, inflammation, and metabolic disorders. By studying the function and regulation of ENTPD5, researchers can gain insights into potential therapeutic targets and develop novel treatments for these conditions. The anti-ENTPD5 Antibody is a valuable tool for investigating the expression and activity of ENTPD5 in different cell types and tissues, making it ideal for studies in molecular biology, biochemistry, and cell physiology.
Product Name:
ENTPD5 Rabbit Monoclonal Antibody
SKU:
CAB19642
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-400 of human ENTPD5 (O75356).
endoplasmic reticulum, extracellular region, extracellular space
Calculated MW:
48kDa
Observed MW:
48kDa
The protein encoded by this gene is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases.
Purification Method:
Affinity purification
Gene ID:
957
Clone Number:
ARC2210
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ENTPD5 Rabbit mAb (CAB19642) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
