The Anti-ELMO1 Antibody (CAB5169) is a polyclonal antibody specifically designed for research involving ELMO1, a protein involved in cell migration and phagocytosis. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications such as Western blotting and immunofluorescence.ELMO1 is a key player in the regulation of Rac GTPases, which are essential for cytoskeletal reorganization during cell movement and phagocytosis. Dysregulation of ELMO1 has been implicated in various diseases, including cancer and autoimmune disorders.
By targeting ELMO1 with this antibody, researchers can better understand its role in disease progression and potentially develop new therapeutic approaches.The Anti-ELMO1 Antibody (CAB5169) is a valuable tool for studies in cell biology, immunology, and cancer research. Its high specificity and sensitivity make it ideal for detecting and analyzing ELMO1 protein expression in various cell types, providing insights into its function and potential as a therapeutic target.
Product Name:
ELMO1 Rabbit Monoclonal Antibody
SKU:
CAB5169
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 628-727 of human ELMO1 (Q92556).
This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
9844
Clone Number:
ARC1985
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ELMO1 Rabbit mAb (CAB5169) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
