The EIF2C3 Polyclonal Antibody (CAB19819) is a valuable tool for researchers studying EIF2C3, a key player in the RNA interference pathway. This antibody, produced in rabbits, offers high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the EIF2C3 protein, this antibody enables precise detection and analysis in various cell types, making it an essential component for studies in molecular biology and genetics.
EIF2C3, also known as Argonaute-3, is crucial for mediating the silencing of target genes through small RNA molecules. Its role in gene regulation and RNA interference pathways highlights its importance in understanding cellular processes and potential therapeutic interventions. By uncovering the mechanisms of EIF2C3 function, researchers can gain insights into disease pathogenesis and explore new strategies for targeted therapies in various genetic disorders and cancer.
Product Name:
eIF2C3 Rabbit Monoclonal Antibody
SKU:
CAB19819
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 721-860 of human eIF2C3 (Q9H9G7).
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
192669
Clone Number:
ARC2345
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using eIF2C3 Rabbit mAb (CAB19819) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
