The Anti-EHMT2 Antibody (CAB19288) offered by Assay Genie is a high-quality research tool designed for the study of EHMT2, a histone-lysine N-methyltransferase enzyme involved in epigenetic regulation. This antibody is raised in rabbits and has been validated for use in various applications, including Western blot and immunohistochemistry.EHMT2, also known as G9a, plays a critical role in gene expression regulation through histone methylation, impacting various cellular processes such as differentiation, development, and disease progression. The Anti-EHMT2 Antibody specifically binds to EHMT2, enabling precise detection and analysis in different cell types, making it a valuable tool for researchers in the fields of epigenetics, cancer biology, and developmental biology.
Understanding the function and regulation of EHMT2 is essential for unraveling its role in various pathological conditions, including cancer and neurodevelopmental disorders. This antibody provides researchers with a reliable tool to investigate the molecular mechanisms underlying EHMT2-mediated processes, ultimately contributing to the advancement of therapeutic strategies targeting epigenetic pathways.
Product Name:
EHMT2 Rabbit Monoclonal Antibody
SKU:
CAB19288
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2-300 of human EHMT2 (Q96KQ7).
This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10919
Clone Number:
ARC2470
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of A375 cells, using EHMT2 antibody (CAB19288) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
