The EHD1 Polyclonal Antibody (CAB3496) is an essential tool for researchers studying EHD1, a protein involved in endocytic recycling and membrane trafficking processes. This antibody, produced in rabbits, has high reactivity towards human samples and has been validated for use in Western blotting applications. By targeting the EHD1 protein, this antibody allows for the detection and analysis of EHD1 in various cell types, making it an excellent choice for studies in cell biology and molecular biology.EHD1 is known for its role in the regulation of endocytic recycling, which is essential for maintaining cellular homeostasis and the proper functioning of organelles.
Dysregulation of EHD1 has been implicated in various diseases, including cancer and neurodegenerative disorders, highlighting the importance of studying this protein in a research setting. By using the EHD1 Polyclonal Antibody, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify novel therapeutic targets.
Product Name:
EHD1 Rabbit Monoclonal Antibody
SKU:
CAB3496
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human EHD1 (Q9H4M9).
This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10938
Clone Number:
ARC2015
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using EHD1 Rabbit mAb (CAB3496) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
