The Anti-EDG2 (LPA-1) Antibody (CAB19671) is a valuable tool for researchers studying EDG2 (LPA-1), a G protein-coupled receptor known to be involved in various cellular processes, including cell proliferation, migration, and survival. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in Western blot and immunohistochemistry applications. By binding to the EDG2 (LPA-1) protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for research in cell biology, pharmacology, and neurology.
EDG2 (LPA-1) is a key player in signaling pathways that control cell functions and is implicated in the pathogenesis of diseases such as cancer and neurological disorders. Its role in mediating responses to lysophosphatidic acid (LPA) underscores its importance in cellular physiology and disease progression. Investigating the function of EDG2 (LPA-1) is essential for developing targeted therapies that manipulate its signaling pathways for therapeutic purposes.
Product Name:
EDG2/LPA-1 Rabbit Monoclonal Antibody
SKU:
CAB19671
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human EDG2/LPA-1 (Q92633).
The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Many transcript variants encoding a few different isoforms have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
1902
Clone Number:
ARC2224
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using EDG2/LPA-1 Rabbit mAb (CAB19671) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
