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EDG2/LPA-1 Rabbit Monoclonal Antibody (CAB19671)

SKU:
CAB19671
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
EDG2
GPR26
Gpcr26
LPA1
Mrec1.3
VZG1
edg-2
rec.1.3
vzg-1
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:EDG2/LPA-1 Rabbit Monoclonal Antibody
SKU:CAB19671
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human EDG2/LPA-1 (Q92633).
Sequence:MAAI STSI PVIS QPQF TAMN EPQC FYNE SIAF FYNR SGKH LATE WNTV SKLV MGLG ITVC IFIM LANL LVMV AIYV NRRF HFPI YYLM ANLA AADF FAGL
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:EDG2; LPA1; VZG1; edg-2; vzg-1; Gpcr26; Mrec1.3; rec.1.3; EDG2/LPA-1
Positive Sample:HeLa,Jurkat,Mouse lung,Mouse brain,Rat brain
Conjugate:Unconjugated
Cellular Localization:cytoplasm, dendritic shaft, dendritic spine, endosome, GABA-ergic synapse, glutamatergic synapse, plasma membrane, postsynaptic membrane, presynaptic membrane
Calculated MW:41kDa
Observed MW:41kDa

The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Many transcript variants encoding a few different isoforms have been identified for this gene.

Purification Method:Affinity purification
Gene ID:1902
Clone Number:ARC2224
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using EDG2/LPA-1 Rabbit mAb (CAB19671) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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